Sensitive HIV-1 DNA Pol Next-Generation Sequencing for the Characterisation of Archived Antiretroviral Drug Resistance

Sensitive HIV-1 DNA Pol Next-Generation Sequencing for the Characterisation of Archived Antiretroviral Drug Resistance

Modern HIV-1 treatment effectively suppresses viral amplification in people living with HIV. However, the persistence of HIV-1 DNA as proviruses integrated into the human genome remains the main barrier to achieving a cure. Next-generation sequencing (NGS) offers increased sensitivity for characteri...

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Bibliographic Details
Main Authors: Johannes C. Botha, Matthew Byott, Moira J. Spyer, Paul R. Grant, Kathleen Gärtner, Wilson X. Chen, James Burton, Alasdair Bamford, Laura J. Waters, Carlo Giaquinto, Anna Turkova, Cindy L. Vavro, Eleni Nastouli
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Viruses
Subjects:
HIV-1
HIV-1 DNA
drug resistance
provirus
NGS
sanger
Online Access:https://www.mdpi.com/1999-4915/15/9/1811

Internet

https://www.mdpi.com/1999-4915/15/9/1811

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