regCNN: identifying Drosophila genome-wide cis-regulatory modules via integrating the local patterns in epigenetic marks and transcription factor binding motifs

regCNN: identifying Drosophila genome-wide cis-regulatory modules via integrating the local patterns in epigenetic marks and transcription factor binding motifs

Transcription regulation in metazoa is controlled by the binding events of transcription factors (TFs) or regulatory proteins on specific modular DNA regulatory sequences called cis-regulatory modules (CRMs). Understanding the distributions of CRMs on a genomic scale is essential for constructing th...

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Bibliographic Details
Main Authors: Tzu-Hsien Yang, Ya-Chiao Yang, Kai-Chi Tu
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
cis-regulatory modules
Transcriptional regulation
Epigenetic regulation
Transcriptional factor binding sites
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037021005249

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http://www.sciencedirect.com/science/article/pii/S2001037021005249

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