Identification of Differential Roles of MicroRNA‐33a and ‐33b During Atherosclerosis Progression With Genetically Modified Mice

Identification of Differential Roles of MicroRNA‐33a and ‐33b During Atherosclerosis Progression With Genetically Modified Mice

Background MicroRNA (miR)‐33 targets cholesterol transporter ATP‐binding cassette protein A1 and other antiatherogenic targets and contributes to atherogenic progression. Its inhibition or deletion is known to result in the amelioration of atherosclerosis in mice. However, mice lack the other member...

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Bibliographic Details
Main Authors: Satoshi Koyama, Takahiro Horie, Tomohiro Nishino, Osamu Baba, Naoya Sowa, Yui Miyasaka, Yasuhide Kuwabara, Tetsushi Nakao, Masataka Nishiga, Hitoo Nishi, Yasuhiro Nakashima, Fumiko Nakazeki, Yuya Ide, Masahiro Kimura, Shuhei Tsuji, Randolph Ruiz Rodriguez, Sijia Xu, Tomohiro Yamasaki, Chiharu Otani, Toshimitsu Watanabe, Tomoyuki Nakamura, Koji Hasegawa, Takeshi Kimura, Koh Ono
Format: Article
Language:English
Published: Wiley 2019-07-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
atherosclerosis
humanized mouse model
lipid metabolism
microRNA
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.119.012609

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https://www.ahajournals.org/doi/10.1161/JAHA.119.012609

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