Human Sensory Neuron-like Cells and Glycated Collagen Matrix as a Model for the Screening of Analgesic Compounds

Human Sensory Neuron-like Cells and Glycated Collagen Matrix as a Model for the Screening of Analgesic Compounds

Increased collagen-derived advanced glycation end-products (AGEs) are consistently related to painful diseases, including osteoarthritis, diabetic neuropathy, and neurodegenerative disorders. We have recently developed a model combining a two-dimensional glycated extracellular matrix (ECM-GC) and pr...

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Bibliographic Details
Main Authors: Michelle Cristiane Bufalo, Maíra Estanislau Soares de Almeida, José Ricardo Jensen, Carlos DeOcesano-Pereira, Flavio Lichtenstein, Gisele Picolo, Ana Marisa Chudzinski-Tavassi, Sandra Coccuzzo Sampaio, Yara Cury, Vanessa Olzon Zambelli
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cells
Subjects:
two-dimensional culture
nociception
inflammatory disease
in vitro assays
analgesic compounds
high-content screening
Online Access:https://www.mdpi.com/2073-4409/11/2/247

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https://www.mdpi.com/2073-4409/11/2/247

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