Disruption of Crystal Packing in Thieno[2,3-<i>b</i>]pyridines Improves Anti-Proliferative Activity
3-Amino-2-arylcarboxamido-thieno[2,3-<i>b</i>]pyridines have been shown to have anti-proliferative activity, but are also known to have poor solubility. This has been previously proposed to be due to their extensive planarity, which allows for intermolecular stacking and crystal packing....
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-01-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/27/3/836 |