Transcriptomic Bioinformatic Analyses of Atria Uncover Involvement of Pathways Related to Strain and Post-translational Modification of Collagen in Increased Atrial Fibrillation Vulnerability in Intensely Exercised Mice

Transcriptomic Bioinformatic Analyses of Atria Uncover Involvement of Pathways Related to Strain and Post-translational Modification of Collagen in Increased Atrial Fibrillation Vulnerability in Intensely Exercised Mice

Atrial Fibrillation (AF) is the most common supraventricular tachyarrhythmia that is typically associated with cardiovascular disease (CVD) and poor cardiovascular health. Paradoxically, endurance athletes are also at risk for AF. While it is well-established that persistent AF is associated with at...

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Bibliographic Details
Main Authors: Yena Oh, Sibao Yang, Xueyan Liu, Sayantan Jana, Farzad Izaddoustdar, Xiaodong Gao, Ryan Debi, Dae-Kyum Kim, Kyoung-Han Kim, Ping Yang, Zamaneh Kassiri, Robert Lakin, Peter H. Backx
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Physiology
Subjects:
atrial fibrillation (AF)
RNA sequencing (RNA-seq)
tumor necrosis factor
inflammation
collagen
mechanotransduction
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2020.605671/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2020.605671/full

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