Effect of tamoxifen in RAFT miniemulsion polymerization during the synthesis of polymer nanoparticles

Effect of tamoxifen in RAFT miniemulsion polymerization during the synthesis of polymer nanoparticles

Tamoxifen (TXF) is currently the only hormonal agent used for treatment of breast cancer. Although very effective, TXF presents low solubility in water, which affects its absorption and bioavailability. A common strategy to overcome this barrier is the formulation of a drug delivery system (DDS) in...

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Bibliographic Details
Main Authors: Tailane Sant'Anna Moreira, Marco Antônio Monteiro de Oliveira, Márcio Nele, José Carlos Pinto, Luis Mauricio Trambaioli da Rocha e Lima
Format: Article
Language:English
Published: Associação Brasileira de Polímeros 2014-01-01
Series:Polímeros
Subjects:
Nanoparticles
drug delivery systems
RAFT polymerization
tamoxifen
methyl methacrylate
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282014000700006&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282014000700006&lng=en&tlng=en

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