Preclinical evaluation of engineered oncolytic herpes simplex virus for the treatment of neuroblastoma.

Preclinical evaluation of engineered oncolytic herpes simplex virus for the treatment of neuroblastoma.

Despite intensive research efforts and therapeutic advances over the last few decades, the pediatric neural crest tumor, neuroblastoma, continues to be responsible for over 15% of pediatric cancer deaths. Novel therapeutic options are needed for this tumor. Recently, investigators have shown that mi...

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Bibliographic Details
Main Authors: Lauren A Gillory, Michael L Megison, Jerry E Stewart, Elizabeth Mroczek-Musulman, Hugh C Nabers, Alicia M Waters, Virginia Kelly, Jennifer M Coleman, James M Markert, G Yancey Gillespie, Gregory K Friedman, Elizabeth A Beierle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3795073?pdf=render

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http://europepmc.org/articles/PMC3795073?pdf=render

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