Synthesis of Pore-Size-Tunable Mesoporous Silica Nanoparticles by Simultaneous Sol-Gel and Radical Polymerization to Enhance Silibinin Dissolution

Background: Silibinin (SBN), a major active constituent of milk thistle seeds, exhibits numerous pharmacological activities. However, its oral bioavailability is low due to poor water solubility. This study aimed to develop a new synthetic approach for tuning the pore characteristics of mesoporous s...

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Bibliographic Details
Main Authors: Mina Shafiee, Samirasadat Abolmaali, Mozhgan Abedanzadeh, Mehdi Abedi, Alimohammad Tamaddon
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2021-11-01
Series:Iranian Journal of Medical Sciences
Subjects:
Online Access:https://ijms.sums.ac.ir/article_47281_1a28e4112937aeb09abd160730afd346.pdf