Using Organoids to Model Sex Differences in the Human Brain

Using Organoids to Model Sex Differences in the Human Brain

Sex differences are widespread during neurodevelopment and play a role in neuropsychiatric conditions such as autism, which is more prevalent in males than females. In humans, males have been shown to have larger brain volumes than females with development of the hippocampus and amygdala showing pro...

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Bibliographic Details
Main Authors: Adam Pavlinek, Dwaipayan Adhya, Alex Tsompanidis, Varun Warrier, Anthony C. Vernon, Madeline Lancaster, Jonathan Mill, Deepak P. Srivastava, Simon Baron-Cohen, Carrie Allison, Rosie Holt, Paula Smith, Tracey Parsons, Joanna Davis, Matthew Hassall, Daniel H. Geschwind, Alexander EP. Heazell, Alice Franklin, Rosie Bamford, Jonathan Davies, Matthew E. Hurles, Hilary C. Martin, Mahmoud Mousa, David H. Rowitch, Kathy K. Niakan, Graham J. Burton, Fateneh Ghafari, Lucia Dutan-Polit, Madeline A. Lancaster, Ilaria Chiaradia, Tal Biron-Shental, Lidia V. Gabis
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Biological Psychiatry Global Open Science
Subjects:
Autism
Brain organoids
Sex chromosomes
Sex differences
Steroids
X chromosome inactivation
Online Access:http://www.sciencedirect.com/science/article/pii/S2667174324000569

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http://www.sciencedirect.com/science/article/pii/S2667174324000569

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