Estimating optimal sparseness of developmental gene networks using a semi-quantitative model.

To estimate gene regulatory networks, it is important that we know the number of connections, or sparseness of the networks. It can be expected that the robustness to perturbations is one of the factors determining the sparseness. We reconstruct a semi-quantitative model of gene networks from gene e...

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Bibliographic Details
Main Authors: Natsuhiro Ichinose, Tetsushi Yada, Hiroshi Wada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5400252?pdf=render