Transcription Factor Lmx1b Negatively Regulates Osteoblast Differentiation and Bone Formation

Transcription Factor Lmx1b Negatively Regulates Osteoblast Differentiation and Bone Formation

The LIM-homeodomain transcription factor Lmx1b plays a key role in body pattern formation during development. Although Lmx1b is essential for the normal development of multiple tissues, its regulatory mechanism in bone cells remains unclear. Here, we demonstrated that Lmx1b negatively regulates bone...

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Bibliographic Details
Main Authors: Kabsun Kim, Jung Ha Kim, Inyoung Kim, Semun Seong, Jeong Eun Han, Keun-Bae Lee, Jeong-Tae Koh, Nacksung Kim
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
Lmx1b
BMP2
Runx2
osteoblast
bone formation
Online Access:https://www.mdpi.com/1422-0067/23/9/5225

Internet

https://www.mdpi.com/1422-0067/23/9/5225

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