The Non-Homologous End Joining Protein PAXX Acts to Restrict HSV-1 Infection

Herpes simplex virus 1 (HSV-1) has extensive interactions with the host DNA damage response (DDR) machinery that can be either detrimental or beneficial to the virus. Proteins in the homologous recombination pathway are known to be required for efficient replication of the viral genome, while differ...

Full description

Bibliographic Details
Main Authors: Ben J. Trigg, Katharina B. Lauer, Paula Fernandes dos Santos, Heather Coleman, Gabriel Balmus, Daniel S. Mansur, Brian J. Ferguson
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/9/11/342