Influence of Humoral Response Against GnRH, Generated by Immunization with a Therapeutic Vaccine Candidate on the Evolution of Patients with Castration-Sensitive Prostate Adenocarcinoma

Background and aims A gonadotropin-releasing hormone (GnRH)-based therapeutic vaccine candidate against hormone-sensitive prostate cancer has demonstrated its safety and signs of efficacy in phase I/II trials. In this study, we characterized the isotype/subclass profiles of the anti-GnRH humoral res...

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Main Authors: Ana Cristina Campal-Espinosa PhD, Jesús Arturo Junco-Barranco PhD, Franklin Fuentes-Aguilar MSc, Lesvia Calzada-Aguilera BSc, Annia Rivacoba-Betancourt MD, Ranfis Humberto Rodríguez-Bueno MD, Ana Claudia Bover-Campal MD, Eddy Emilio Bover-Fuentes MSc, Lourdes González BSc, Lourdes de Quesada MSc, Allelin Alvarez BSc, Hilda Elisa Garay-Pérez PhD
Format: Article
Language:English
Published: SAGE Publishing 2023-10-01
Series:Technology in Cancer Research & Treatment
Online Access:https://doi.org/10.1177/15330338231207318