Molecular Chaperones’ Potential against Defective Proteostasis of Amyotrophic Lateral Sclerosis

Molecular Chaperones’ Potential against Defective Proteostasis of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a neuronal degenerative condition identified via a build-up of mutant aberrantly folded proteins. The native folding of polypeptides is mediated by molecular chaperones, preventing their pathogenic aggregation. The mutant protein expression in ALS is linked wit...

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Bibliographic Details
Main Authors: Sumit Kinger, Ankur Rakesh Dubey, Prashant Kumar, Yuvraj Anandrao Jagtap, Akash Choudhary, Amit Kumar, Vijay Kumar Prajapati, Rohan Dhiman, Amit Mishra
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Cells
Subjects:
ALS
chaperones
HSP70
HSP27
HSPB8
HSP40
Online Access:https://www.mdpi.com/2073-4409/12/9/1302

Internet

https://www.mdpi.com/2073-4409/12/9/1302

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