Synthesis, Molecular Structure and Spectroscopic Investigations of Novel Fluorinated Spiro Heterocycles

Synthesis, Molecular Structure and Spectroscopic Investigations of Novel Fluorinated Spiro Heterocycles

This paper describes an efficient and regioselective method for the synthesis of novel fluorinated spiro-heterocycles in excellent yield by cascade [5+1] double Michael addition reactions. The compounds 7,11-bis(4-fluorophenyl)-2,4-dimethyl- 2,4-diazaspiro[5.5] undecane-1,3,5,9-tetraone (3a) and 2,4...

Full description

Bibliographic Details
Main Authors: Mohammad Shahidul Islam, Abdullah Mohammed Al-Majid, Assem Barakat, Saied M. Soliman, Hazem A. Ghabbour, Ching Kheng Quah, Hoong-Kun Fun
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:Molecules
Subjects:
fluorine spiro-heterocycles
[5+1] cycloaddition
N,N-dimethylbarbituric acid
X-ray
DFT
Online Access:http://www.mdpi.com/1420-3049/20/5/8223

Internet

http://www.mdpi.com/1420-3049/20/5/8223

Similar Items