Investigating the Effect of Aspirin on apoAI-Induced ATP Binding Cassette Transporter 1 Protein Expression and Cholesterol Efflux in Human Astrocytes

Investigating the Effect of Aspirin on apoAI-Induced ATP Binding Cassette Transporter 1 Protein Expression and Cholesterol Efflux in Human Astrocytes

Background: Neurons need a high amount of cholesterol to maintain the stability of their membrane-rich structures. Astrocytes synthesize and distribute cholesterol to neurons, and ABCA1 is a key mediator of cholesterol efflux to generate HDL for cholesterol transport in the brain. Several studies im...

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Bibliographic Details
Main Authors: Zahra Nazeri, Neda Abdeveiszadeh, Vahid Zarezade, Shirin Azizidoost, Maryam Cheraghzadeh, Mohammad Aberumand, Alireza Kheirollah
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-02-01
Series:Advanced Biomedical Research
Subjects:
abca1
apolipoprotein a-i
aspirin
astrocytes
cholesterol
Online Access:https://journals.lww.com/10.4103/abr.abr_417_22

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https://journals.lww.com/10.4103/abr.abr_417_22

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