A novel approach to exploring the dark genome and its application to mapping of the vertebrate virus fossil record

Abstract Background Genomic regions that remain poorly understood, often referred to as the dark genome, contain a variety of functionally relevant and biologically informative features. These include endogenous viral elements (EVEs)—virus-derived sequences that can dramatically impact host biology...

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Bibliographic Details
Main Authors: Daniel Blanco-Melo, Matthew A. Campbell, Henan Zhu, Tristan P. W. Dennis, Sejal Modha, Spyros Lytras, Joseph Hughes, Anna Gatseva, Robert J. Gifford
Format: Article
Language:English
Published: BMC 2024-05-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-024-03258-y