Go Green: The Antiinflammatory Effects of Biliverdin Reductase

Biliverdin (BV) has emerged as a cytoprotective and important anti-inflammatory molecule. Conversion of BV to bilirubin (BR) is catalyzed by biliverdin reductase (BVR) and is required for the downstream signaling and nuclear localization of BVR. Recent data by others and us make clear that BVR is a...

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Bibliographic Details
Main Authors: Barbara eWegiel, Leo eOtterbein
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-03-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00047/full