Physicochemical mechanisms of protein regulation by phosphorylation

Phosphorylation offers a dynamic way to regulate protein activity and subcellular localization, which is achieved through reversibility and fast kinetics of posttranslational modifications. Adding or removing a dianionic phosphate group somewhere on a protein often changes the protein’s structural p...

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Bibliographic Details
Main Authors: Hafumi eNishi, Alexey eShaytan, Anna R. Panchenko
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00270/full