Chemokine receptor co-expression reveals aberrantly distributed TH effector memory cells in GPA patients

Chemokine receptor co-expression reveals aberrantly distributed TH effector memory cells in GPA patients

Abstract Background Persistent expansion of circulating CD4+ effector memory T cells (TEM) in patients with granulomatosis with polyangiitis (GPA) suggests their fundamental role in disease pathogenesis. Recent studies have shown that distinct functional CD4+ TEM cell subsets can be identified based...

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Bibliographic Details
Main Authors: Lucas L. Lintermans, Abraham Rutgers, Coen A. Stegeman, Peter Heeringa, Wayel H. Abdulahad
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Arthritis Research & Therapy
Subjects:
Vasculitis
Granulomatosis with polyangiitis
TH cells
Effector memory TH cells
Chemokine receptors
Online Access:http://link.springer.com/article/10.1186/s13075-017-1343-8

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http://link.springer.com/article/10.1186/s13075-017-1343-8

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