Influence of Bile Acids in Hydrogel Pharmaceutical Formulations on Dissolution Rate and Permeation of Clindamycin Hydrochloride

Influence of Bile Acids in Hydrogel Pharmaceutical Formulations on Dissolution Rate and Permeation of Clindamycin Hydrochloride

Clindamycin hydrochloride is a widely used antibiotic for topical use, but its main disadvantage is poor skin penetration. Therefore, new approaches in the development of clindamycin topical formulations are of great importance. We aimed to investigate the effects of the type of gelling agent (carbo...

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Bibliographic Details
Main Authors: Nebojša Pavlović, Isidora Anastasija Bogićević, Dragana Zaklan, Maja Đanić, Svetlana Goločorbin-Kon, Hani Al-Salami, Momir Mikov
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Gels
Subjects:
topical drug
clindamycin
permeability
flux
gel
Online Access:https://www.mdpi.com/2310-2861/8/1/35

Internet

https://www.mdpi.com/2310-2861/8/1/35

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