Characterization of antigen-specific CD8+ memory T cell subsets in peripheral blood of patients with multiple sclerosis

Characterization of antigen-specific CD8+ memory T cell subsets in peripheral blood of patients with multiple sclerosis

BackgroundIncreasing evidence indicates the importance of CD8+ T cells in autoimmune attack against CNS myelin and axon in multiple sclerosis (MS). Previous research has also discovered that myelin-reactive T cells have memory phenotype functions in MS patients. However, limited evidence is availabl...

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Main Authors: Pen-Ju Liu, Ting-Ting Yang, Ze-Xin Fan, Guo-Bin Yuan, Lin Ma, Ze-Yi Wang, Jian-Feng Lu, Bo-Yi Yuan, Wen-Long Zou, Xing-Hu Zhang, Guang-Zhi Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
multiple sclerosis
peripheral blood mononuclear cells
memory T cells
oligodendrocyte glycoprotein
pentamer
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1110672/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1110672/full

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