A spectrum of pleiotropic consequences in development due to changes in a regulatory pathway.

Regulatory evolution has frequently been proposed as the primary mechanism driving morphological evolution. This is because regulatory changes may be less likely to cause deleterious pleiotropic effects than changes in protein structure, and consequently have a higher likelihood to be beneficial. We...

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Bibliographic Details
Main Authors: Ana E Escalante, Sumiko Inouye, Michael Travisano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3427377?pdf=render