Real-time whole-brain imaging of hemodynamics and oxygenation at micro-vessel resolution with ultrafast wide-field photoacoustic microscopy

The ultrafast wide-field photoacoustic microscopy integrates novel light source, fast scanning mechanism, and machine learning enhancement, which allows high-speed tracking of whole-brain functions in action at capillary level.

Bibliographic Details
Main Authors: Xiaoyi Zhu, Qiang Huang, Anthony DiSpirito, Tri Vu, Qiangzhou Rong, Xiaorui Peng, Huaxin Sheng, Xiling Shen, Qifa Zhou, Laiming Jiang, Ulrike Hoffmann, Junjie Yao
Format: Article
Language:English
Published: Nature Publishing Group 2022-05-01
Series:Light: Science & Applications
Online Access:https://doi.org/10.1038/s41377-022-00836-2