Modulation of insulin secretion by RBFOX2-mediated alternative splicing

Abstract Insulin secretion is a tightly regulated process that is vital for maintaining blood glucose homeostasis. Although the molecular components of insulin granule trafficking and secretion are well established, how they are regulated to rapidly fine-tune secretion in response to changing enviro...

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Bibliographic Details
Main Authors: Nicole D. Moss, Kristen L. Wells, Alexandra Theis, Yong-Kyung Kim, Aliya F. Spigelman, Xiong Liu, Patrick E. MacDonald, Lori Sussel
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43605-4