Protocol for in vivo and ex vivo assessment of hyperglycemia and islet function in diabetic mice

Summary: Mouse hyperglycemia model and islet function assessment are essential in diabetes research. Here, we provide a protocol to evaluate glucose homeostasis and islet functions in diabetic mice and isolated islets. We describe steps for establishing type 1 and 2 diabetes, glucose tolerance test,...

Full description

Bibliographic Details
Main Authors: Hao Chen, Jian Liu, Guo-Ping Shi, Xian Zhang
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166723000916