Loss of anti-viral immunity by infection with a virus encoding a cross-reactive pathogenic epitope.

T cell cross-reactivity between different strains of the same virus, between different members of the same virus group, and even between unrelated viruses is a common occurrence. We questioned here how an intervening infection with a virus containing a sub-dominant cross-reactive T cell epitope woul...

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Bibliographic Details
Main Authors: Alex T Chen, Markus Cornberg, Stephanie Gras, Carole Guillonneau, Jamie Rossjohn, Andrew Trees, Sebastien Emonet, Juan C de la Torre, Raymond M Welsh, Liisa K Selin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3334890?pdf=render