Gene expression profile of ABC transporters and cytotoxic effect of ibuprofen and acetaminophen in an epithelial ovarian cancer cell line in vitro

Gene expression profile of ABC transporters and cytotoxic effect of ibuprofen and acetaminophen in an epithelial ovarian cancer cell line in vitro

PURPOSES: To determine the basic expression of ABC transporters in an epithelial ovarian cancer cell line, and to investigate whether low concentrations of acetaminophen and ibuprofen inhibited the growth of this cell line in vitro. METHODS: TOV-21 G cells were exposed to different concentrations of...

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Bibliographic Details
Main Authors: Renilton Aires Lima, Eduardo Batista Cândido, Flávia Perrim de Melo, Josiane Barbosa Piedade, Paula Vieira Teixeira Vidigal, Luciana Maria Silva, Agnaldo Lopes da Silva Filho
Format: Article
Language:English
Published: Federação Brasileira das Sociedades de Ginecologia e Obstetrícia 2015-06-01
Series:Revista Brasileira de Ginecologia e Obstetrícia
Subjects:
Acetaminophen
Apoptosis
ATP-binding cassette transporters
Cell proliferation
Chemoprevention
Drug therapy
Ibuprofen
Ovarian neoplasms
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032015000600283&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032015000600283&tlng=en

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