Honduras HIV cohort: HLA class I and CCR5-Δ32 profiles and their associations with HIV disease outcome

Honduras HIV cohort: HLA class I and CCR5-Δ32 profiles and their associations with HIV disease outcome

ABSTRACT Human leukocyte antigen (HLA) polymorphisms represent the strongest genetic modifier of HIV disease progression. Diverse HLA distributions can lead to distinct HIV control landscapes at the population level. We aimed to describe HLA allele and haplotype frequencies (linkage disequilibrium,...

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Bibliographic Details
Main Authors: Humberto Valenzuela-Ponce, Candy Carbajal, Maribel Soto-Nava, Daniela Tapia-Trejo, Claudia García-Morales, Wendy Murillo, Ivette Lorenzana, Gustavo Reyes-Terán, Santiago Ávila-Ríos
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:Microbiology Spectrum
Subjects:
HLA allele frequencies
HLA haplotype structures
HLA linkage disequilibrium
HLA-HIV disease associations
Honduran Mestizos
Latin America
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01613-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.01613-23

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