Linked optical and gene expression profiling of single cells at high-throughput

Abstract Single-cell RNA sequencing has emerged as a powerful tool for characterizing cells, but not all phenotypes of interest can be observed through changes in gene expression. Linking sequencing with optical analysis has provided insight into the molecular basis of cellular function, but current...

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Bibliographic Details
Main Authors: Jesse Q. Zhang, Christian A. Siltanen, Leqian Liu, Kai-Chun Chang, Zev J. Gartner, Adam R. Abate
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Genome Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13059-020-01958-9