Mechanisms of Immune Tolerance in Liver Transplantation-Crosstalk Between Alloreactive T Cells and Liver Cells With Therapeutic Prospects

Mechanisms of Immune Tolerance in Liver Transplantation-Crosstalk Between Alloreactive T Cells and Liver Cells With Therapeutic Prospects

Liver transplantation (LTx) is currently the most powerful treatment for end-stage liver disease. Although liver allograft is more tolerogenic compared to other solid organs, the majority of LTx recipients still require long-term immune suppression (IS) to control the undesired alloimmune responses,...

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Bibliographic Details
Main Authors: Hong Lei, Petra Reinke, Hans-Dieter Volk, Yi Lv, Rongqian Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
liver transplantation
alloreactive T cells
crosstalk
liver cells
tolerance induction
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02667/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02667/full

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