Surveillance of Daughter Micronodule Formation Is a Key Factor for Vaccine Evaluation Using Experimental Infection Models of Tuberculosis in Macaques

Surveillance of Daughter Micronodule Formation Is a Key Factor for Vaccine Evaluation Using Experimental Infection Models of Tuberculosis in Macaques

Tuberculosis (TB) is still a major worldwide health problem and models using non-human primates (NHP) provide the most relevant approach for vaccine testing. In this study, we analysed CT images collected from cynomolgus and rhesus macaques following exposure to ultra-low dose <i>Mycobacterium...

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Bibliographic Details
Main Authors: Isabel Nogueira, Martí Català, Andrew D. White, Sally A Sharpe, Jordi Bechini, Clara Prats, Cristina Vilaplana, Pere-Joan Cardona
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pathogens
Subjects:
tuberculosis
BCG vaccine
aerosol vaccination
non-human primate
macaque
bubble model
Online Access:https://www.mdpi.com/2076-0817/12/2/236

Internet

https://www.mdpi.com/2076-0817/12/2/236

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