A genomic pathway approach to a complex disease: axon guidance and Parkinson disease.

A genomic pathway approach to a complex disease: axon guidance and Parkinson disease.

While major inroads have been made in identifying the genetic causes of rare Mendelian disorders, little progress has been made in the discovery of common gene variations that predispose to complex diseases. The single gene variants that have been shown to associate reproducibly with complex disease...

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Bibliographic Details
Main Authors: Timothy G Lesnick, Spiridon Papapetropoulos, Deborah C Mash, Jarlath Ffrench-Mullen, Lina Shehadeh, Mariza de Andrade, John R Henley, Walter A Rocca, J Eric Ahlskog, Demetrius M Maraganore
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1904362?pdf=render

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http://europepmc.org/articles/PMC1904362?pdf=render

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