A genomic pathway approach to a complex disease: axon guidance and Parkinson disease.
While major inroads have been made in identifying the genetic causes of rare Mendelian disorders, little progress has been made in the discovery of common gene variations that predispose to complex diseases. The single gene variants that have been shown to associate reproducibly with complex disease...
Main Authors: | Timothy G Lesnick, Spiridon Papapetropoulos, Deborah C Mash, Jarlath Ffrench-Mullen, Lina Shehadeh, Mariza de Andrade, John R Henley, Walter A Rocca, J Eric Ahlskog, Demetrius M Maraganore |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-06-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC1904362?pdf=render |
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