Change of Cystine/Glutamate Antiporter Expression in Ethanol-Dependent Rats

Background: Some drugs of abuse down regulate the expression of cystine/glutamate (xCT) antiporter in the nucleus accumbens (Acb) after extinction or withdrawal. The altered level of xCT exchanger in Acb, a structure involved in ethanol reinforcement, may contribute to the pathological glutamatergic...

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Bibliographic Details
Main Authors: Alessandra Tiziana Peana, Giulia eMuggironi, Federico eBennardini
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2014.00311/full