Cell-based therapeutic strategies for treatment of spinocerebellar ataxias: an update

Cell-based therapeutic strategies for treatment of spinocerebellar ataxias: an update

Spinocerebellar ataxias are heritable neurodegenerative diseases caused by a cytosine-adenine-guanine expansion, which encodes a long glutamine tract (polyglutamine) in the respective wild-type protein causing misfolding and protein aggregation. Clinical features of polyglutamine spinocerebellar ata...

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Bibliographic Details
Main Authors: Joana Sofia Correia, Sara Duarte-Silva, António José Salgado, Patrícia Maciel
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Neural Regeneration Research
Subjects:
cell transplantation; engraftment; induced pluripotent stem cells; mesenchymal stem cells; neural progenitor cells; neuroprotection; polyglutamine spinocerebellar ataxias; secretome; spinocerebellar ataxia; stem cell therapy
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=6;spage=1203;epage=1212;aulast=Correia

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=6;spage=1203;epage=1212;aulast=Correia

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