Mitochondria-associated programmed cell death as a therapeutic target for age-related disease

Abstract Mitochondria, ubiquitous double-membrane-bound organelles, regulate energy production, support cellular activities, harbor metabolic pathways, and, paradoxically, mediate cell fate. Evidence has shown mitochondria as points of convergence for diverse cell death-inducing pathways that trigge...

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Bibliographic Details
Main Authors: Thanh T. Nguyen, Shibo Wei, Thu Ha Nguyen, Yunju Jo, Yan Zhang, Wonyoung Park, Karim Gariani, Chang-Myung Oh, Hyeon Ho Kim, Ki-Tae Ha, Kyu Sang Park, Raekil Park, In-Kyu Lee, Minho Shong, Riekelt H. Houtkooper, Dongryeol Ryu
Format: Article
Language:English
Published: Nature Publishing Group 2023-08-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-01046-5