Type I Interferon-Induced TMEM106A Blocks Attachment of EV-A71 Virus by Interacting With the Membrane Protein SCARB2

Type I Interferon-Induced TMEM106A Blocks Attachment of EV-A71 Virus by Interacting With the Membrane Protein SCARB2

Enterovirus A71 (EV-A71) and Coxsackievirus A16 (CV-A16) are the main causative agents of hand, foot and mouth disease (HFMD) worldwide. Studies showed that EV-A71 and CV-A16 antagonize the interferon (IFN) signaling pathway; however, how IFN controls this viral infection is largely unknown. Here, w...

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Bibliographic Details
Main Authors: Xuemin Guo, Shinuan Zeng, Xiaoxin Ji, Xiaobin Meng, Nanfeng Lei, Hai Yang, Xin Mu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Immunology
Subjects:
interferon-stimulated gene
enterovirus A71
TMEM106A
SCARB2
antiviral activity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.817835/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.817835/full

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