Blocking the PI3K/AKT Pathway Enhances Mammalian Reovirus Replication by Repressing IFN-stimulated Genes
Many host cellular signaling pathways were activated and exploited by virus infection for more efficient replication. The PI3K/Akt pathway has recently attracted considerable interest due to its role in regulating virus replication. This study demonstrated for the first time that the mammalian reovi...
Main Authors: | Jin eTian, Xiaozhan eZhang, Hongxia eWu, Chunguo eLiu, Zhijie eLi, Xiaoliang eHu, Shuo eSu, Linfa eWang, Liandong eQu |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-09-01
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Series: | Frontiers in Microbiology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00886/full |
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