Low doses of ionizing radiation promote tumor growth and metastasis by enhancing angiogenesis.

Radiotherapy is a widely used treatment option in cancer. However, recent evidence suggests that doses of ionizing radiation (IR) delivered inside the tumor target volume, during fractionated radiotherapy, can promote tumor invasion and metastasis. Furthermore, the tissues that surround the tumor ar...

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Bibliographic Details
Main Authors: Inês Sofia Vala, Leila R Martins, Natsuko Imaizumi, Raquel J Nunes, José Rino, François Kuonen, Lara M Carvalho, Curzio Rüegg, Isabel Monteiro Grillo, João Taborda Barata, Marc Mareel, Susana Constantino Rosa Santos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2888592?pdf=render