HLA genotyping by next-generation sequencing of complementary DNA

HLA genotyping by next-generation sequencing of complementary DNA

Abstract Background Genotyping of the human leucocyte antigen (HLA) is indispensable for various medical treatments. However, unambiguous genotyping is technically challenging due to high polymorphism of the corresponding genomic region. Next-generation sequencing is changing the landscape of genoty...

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Bibliographic Details
Main Authors: Hidenobu Segawa, Yoji Kukita, Kikuya Kato
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Genomics
Subjects:
Next-generation sequencing
cDNA
HLA
Molecular barcode
Online Access:http://link.springer.com/article/10.1186/s12864-017-4300-7

Internet

http://link.springer.com/article/10.1186/s12864-017-4300-7

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