Overexpression of RORγt Enhances Pulmonary Inflammation after Infection with Mycobacterium Avium.

Mycobacterium avium complex (MAC) is the most common cause of nontuberculous mycobacterial disease in humans. The role of Th17 immunity in the pathogenesis of intracellular bacteria, such as MAC, is not currently understood. Transcription factor RAR-related orphan receptor gamma t (RORγt) is known a...

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Bibliographic Details
Main Authors: Masashi Matsuyama, Yukio Ishii, Hirofumi Sakurai, Satoshi Ano, Yuko Morishima, Keigyou Yoh, Satoru Takahashi, Kenji Ogawa, Nobuyuki Hizawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4718649?pdf=render