A trial design to maximize knowledge of the effects of rodatristat ethyl in the treatment of pulmonary arterial hypertension (ELEVATE 2)

Abstract Serotonin plays a key role in the development and maintenance of the pathobiology associated with pulmonary arterial hypertension (PAH). Platelet‐driven and locally produced serotonin from lung tissue and arterial endothelial cells induce excessive growth of pulmonary artery smooth muscle c...

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Bibliographic Details
Main Authors: Howard M. Lazarus, Jill Denning, Stephen Wring, Michelle Palacios, Sidra Hoffman, Katelyn Crizer, Watiri Kamau‐Kelley, William Symonds, Jeremy Feldman
Format: Article
Language:English
Published: Wiley 2022-04-01
Series:Pulmonary Circulation
Subjects:
Online Access:https://doi.org/10.1002/pul2.12088