Associations between expression of indoleamine 2, 3-dioxygenase enzyme and inflammatory cytokines in patients with first-episode drug-naive Schizophrenia

Abstract The indoleamine 2,3-dioxygenase (IDO) enzyme is the first rate-limiting enzyme of the tryptophan degradation pathway in which dysfunction of neuroactive metabolites has been implicated in the pathophysiology of schizophrenia. Inflammatory molecules such as pro-inflammatory cytokines could e...

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Bibliographic Details
Main Authors: Yan Zhang, Han Shi, Ge Yang, Yongfeng Yang, Wenqiang Li, Meng Song, Minglong Shao, Xi Su, Luxian Lv
Format: Article
Language:English
Published: Nature Publishing Group 2021-11-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01688-x