A Facile Synthesis of Functionalized Dispirooxindole Derivatives via a Three-Component 1,3-Dipolar Cycloaddition Reaction

A Facile Synthesis of Functionalized Dispirooxindole Derivatives via a Three-Component 1,3-Dipolar Cycloaddition Reaction

An efficient synthesis of novel dispirooxindoles has been achieved through three-component 1,3-dipolar cycloaddition of azomethine ylides generated in situ by the decarboxylative condensation of isatin and an α-amino acid with the dipolarophile 5-benzylideneimidazolidine-2,4-dione. The improved proc...

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Bibliographic Details
Main Authors: Liang Ouyang, Rongsheng Tong, Jianyou Shi, Zhixiang Yuan, Guang Ouyang, Jun He
Format: Article
Language:English
Published: MDPI AG 2013-05-01
Series:Molecules
Subjects:
multicomponent reactions
1,3-dipolar cycloaddition
azomethine ylide
dispirooxindole
Online Access:http://www.mdpi.com/1420-3049/18/5/5142

Internet

http://www.mdpi.com/1420-3049/18/5/5142

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