LncRNA ZFAS1 regulates the proliferation, oxidative stress, fibrosis, and inflammation of high glucose-induced human mesangial cells via the miR-588/ROCK1 axis

LncRNA ZFAS1 regulates the proliferation, oxidative stress, fibrosis, and inflammation of high glucose-induced human mesangial cells via the miR-588/ROCK1 axis

Abstract Background Diabetic nephropathy (DN) is a critical and the most common microvascular complication and its pathogenesis is still faintly understood. Thus, this study was performed to examine the long non-coding RNA ZNFX1 Antisense Gene Protein 1 (lncRNA ZFAS1) biological function and mechani...

Full description

Bibliographic Details
Main Authors: Zhuang Geng, Bingzi Dong, Wenshan Lv, Zhongchao Wang, Xiang Wang, YaJing Huang, Yangang Wang, Lili Xu
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Diabetic nephropathy
Mesangial cells
Fibrosis
ZFAS1
miR-588
ROCK1
Online Access:https://doi.org/10.1186/s13098-022-00791-3

Internet

https://doi.org/10.1186/s13098-022-00791-3

Similar Items