Unravelling B cell heterogeneity: insights into flow cytometry-gated B cells from single-cell multi-omics data

IntroductionB cells play a pivotal role in adaptive immunity which has been extensively characterised primarily via flow cytometry-based gating strategies. This study addresses the discrepancies between flow cytometry-defined B cell subsets and their high-confidence molecular signatures using single...

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Bibliographic Details
Main Authors: Jane I. Pernes, Atheer Alsayah, Felicia Tucci, Rachael J. M. Bashford-Rogers
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1380386/full