Markers of extracellular matrix remodeling and systemic inflammation in patients with heritable thoracic aortic diseases

Markers of extracellular matrix remodeling and systemic inflammation in patients with heritable thoracic aortic diseases

BackgroundIn approximately 20% of patients with thoracic aortic aneurysms or dissections a heritable thoracic aortic disease (HTAD) is suspected. Several monogenic connective tissue diseases imply high risk of aortic disease, including both non-syndromic and syndromic forms. There are some studies a...

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Bibliographic Details
Main Authors: Bjørn Edvard Seim, Margrethe Flesvig Holt, Aleksandra Ratajska, Annika Michelsen, Monica Myklebust Ringseth, Bente Evy Halvorsen, Mona Skjelland, John-Peder Escobar Kvitting, Runar Lundblad, Kirsten Krohg-Sørensen, Liv T. N. Osnes, Pål Aukrust, Benedicte Paus, Thor Ueland
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
heritable thoracic aortic disease
inflammation
extracellular matrix (ECM)
connective tissue disease (CTD)/collagen vascular disease (CVD)
Loeys-Dietz syndrome
Marfan syndrome
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.1073069/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.1073069/full

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