A Validated RP-HPLC Method for the Determination of Butamirate Citrate and Benzoic Acid in Syrup, Based on an Experimental Design Assessment of Robustness

A reversed-phase high-pressure liquid chromatography (RP-HPLC) method was developed and subsequently validated for the simultaneous determination of butamirate citrate (BC) and benzoic acid (BA) in cough syrup. The separation was performed employing a cyanopropyl column with a mobile phase consistin...

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Bibliographic Details
Main Authors: Antonios-Dionysios G. Neofotistos, Kostas Gkountanas, Haris Boutsikaris, Yannis Dotsikas
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Separations
Subjects:
Online Access:https://www.mdpi.com/2297-8739/8/10/163